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Research Areas：
Proteases
Apoptosis
Chromatin/Epigenetics
Metabolism
MAPK Signaling
Tyrosine Kinase
DNA Damage/DNA Repair
PI3K/Akt/mTOR
Microbiology & Virology
Ubiquitination/ Proteasome
JAK/STAT Signaling
TGF-β / Smad Signaling
Angiogenesis
GPCR/G protein
Endocrinology and Hormones
Immunology/Inflammation
Neuroscience
Membrane Transporter/Ion Channel
Others
Antibody-drug Conjugate/ADC Related
Antioxidants
Peptides
Default
Research Grade Biosimilar
ATPase
Cancer Biology
Cell Cycle/Checkpoint
Epigenetics
Infectious Disease
Natural Products
Active Pharmaceutical Ingredients
PROTAC
Stem Cell
Signaling Pathways：
Wnt/β-catenin
Oct3/4
Notch
GSK-3
Hedgehog/Smoothened inhibitor
Cyclopamine-KAAD （CAS#306387-90-6 Cat#D943346）
CAS#：
306387-90-6
Formula：
C₄₄H₆₃N₃O₄
Molecular Weight：
698
Solubility：
Chloroform: Slightly soluble,Methanol: Slightly soluble
Biological Target：
Cyclopamine-KAAD is a potent inhibitor of hedgehog signaling with an IC50 value of 20 nM in a Shh-LIGHT2 assay.
Storage：
Store at -20°C
Hedgehog/Smoothened inhibitor
$746.00
万
IWR-1-endo （CAS#1127442-82-3 Cat#D910950）
CAS#：
1127442-82-3
Formula：
C₂₅H₁₉N₃O₃
Molecular Weight：
409.44
Solubility：
≥ 20.45mg/mL in DMSO
Biological Target：
Potent Wnt signaling inhibitor
Storage：
Store at -20°C
Wnt/β-catenin
$60.00
万
CUR 61414 （CAS#334998-36-6 Cat#D911217）
CAS#：
334998-36-6
Formula：
C₃₁H₄₂N₄O₅
Molecular Weight：
550.7
Solubility：
≤10mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide
Biological Target：
potent inhibitor of hedgehog-induced cellular activity
Storage：
Store at -20°C
Hedgehog/Smoothened inhibitor
$186.00
万
KYA1797K （CAS#1956356-56-1 Cat#D919216）
CAS#：
1956356-56-1
Formula：
C₁₇H₁₁KN₂O₆S₂
Molecular Weight：
442.51
Solubility：
DMSO : 6 mg/mL (13.56 mM);H2O : 1 mg/mL (2.26 mM)
Biological Target：
A potent and selective Wnt/β-catenin inhibitor
Storage：
Store at -20°C
Wnt/β-catenin
$90.00
万
IWP-3 （CAS#687561-60-0 Cat#D917071）
CAS#：
687561-60-0
Formula：
C₂₂H₁₇FN₄O₂S₃
Molecular Weight：
484.6
Solubility：
≤0.1mg/ml in DMSO;2mg/ml in dimethyl formamide
Biological Target：
inhibitor of Wnt production
Storage：
Store at -20°C
Wnt/β-catenin
$92.00
万
WIKI4 （CAS#838818-26-1 Cat#D911674）
CAS#：
838818-26-1
Formula：
C₂₉H₂₃N₅O₃S
Molecular Weight：
521.59
Solubility：
≥ 26.1mg/mL in DMSO with gentle warming
Biological Target：
Inhibitor of Wnt/ß-Catenin signaling and tankyrase
Storage：
Store at -20°C
Wnt/β-catenin
$104.00
万
LY-900009 （CAS#209984-68-9 Cat#D919492）
CAS#：
209984-68-9
Formula：
C₂₃H₂₇N₃O₄
Molecular Weight：
409.48
Solubility：
Soluble in DMSO
Biological Target：
LY-900009 is a potent inhibitor of Notch with IC50 value of 0.27 nM.
Storage：
Store at -20°C
Notch
$202.00
万
AZD2858 （CAS#486424-20-8 Cat#D914736）
CAS#：
486424-20-8
Formula：
C₂₁H₂₃N₇O₃S
Molecular Weight：
453.52
Solubility：
≥ 11.35mg/mL in DMSO
Biological Target：
GSK-3 inhibitor,potent and selective
Storage：
Store at -20° C
GSK-3
$91.00
万
CCT 031374 hydrobromide （CAS#1219184-91-4 Cat#D910253）
CAS#：
1219184-91-4
Formula：
C₂₃H₁₉N₃O.HBr
Molecular Weight：
434.33
Solubility：
<21.72mg/ml in DMSO
Biological Target：
inhibits TCF-dependent transcription, blocks BIO-induced β-catenin stabilization
Storage：
Desiccate at RT
Wnt/β-catenin
$322.00
万
Indirubin （CAS#479-41-4 Cat#D912975）
CAS#：
479-41-4
Formula：
C₁₆H₁₀N₂O₂
Molecular Weight：
262.26
Solubility：
DMF: 1 mg/ml,DMSO: 1 mg/ml
Biological Target：
A cyclin-dependent kinases and GSK-3β inhibitor
Storage：
Store at -20°C
GSK-3
$37.00
万
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